Attribut:Has abstract
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Hello World! provides a gentle but thorough introduction to the world of computer programming. +
Hello! Flex 4 progresses through 26 self-contained examples selected so you can progressively master Flex. They vary from small one-page apps, to a 3D rotating haiku, to a Connect Four-like game. And in the last chapter you'll learn to build a full Flex application called SocialStalkr a mashup that lets you follow your friends by showing their tweets on a Yahoo map. +
Quick and Easy HTML5 and CSS3 is written for the web designer or developer who wants a fast, example-oriented introduction to the new HTML and CSS features. After a quick review of the basics, you'll turn to what's new. Start by learning to apply important new elements and attributes by building your first real HTML5 pages. You'll then take a quick tour through the new APIs: Form Validation, Canvas, Drag & Drop, Geolocation and Offline Applications. You'll also discover how to include video and audio on your pages without plug-ins, and how to draw interactive vector graphics with SVG. +
Hello! Python fully covers the building blocks of Python programming and gives you a gentle introduction to more advanced topics such as object oriented programming, functional programming, network programming, and program design. New (or nearly new) programmers will learn most of what they need to know to start using Python immediately. +
Sailor Ishmael tells the story of the obsessive quest of Ahab, captain of the whaler the Pequod, for revenge on Moby Dick, the white whale that on the previous whaling voyage bit off Ahab's leg at the knee. +
"If you want to learn Hibernate quickly, this book shows you step by step." - Sang Shin, Java Technology Architect, Sun Microsystems +
"A great resource for true database independent full text search." --Aaron Walker, base2Services +
"2005 Best Java Book!" -- Java Developer's Journal +
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Gets new users going and gives experienced users in-depth coverage of advanced features. Jeff Cunningham, The Weather Channel Interactive +
iOS 4 in Action, written for Xcode 4, is a detailed, hands-on guide that goes from setting up your development environment, through your first coding steps, all the way to creating a polished, commercial iOS 4 application. You'll run through examples from a variety of areas including a chat client, a video game, an interactive map, and background audio. You'll also learn how the new iOS 4 features apply to your existing iOS 3 based apps. This book will help you become a confident, well-rounded iOS 4 developer. +
Using many examples, the book covers core features like accelerometers, GPS, the Address Book, and much more. Along the way, you'll learn to leverage your iPhone skills to build attractive iPad apps. This is a revised and expanded edition of the original iPhone in Action. +
There is not another iPhone title that does such a great coverage of both Web and SDK topics under one roof, thus providing a well-rounded developer education. Vladimir Pasman, Cocoacast.com +
"I've been using iText for over a year, but I still learnt an awful lot while reading this book." --JavaLobby +
iText in Action, Second Edition offers an introduction and a practical guide to iText and the internals of PDF. While at the entry level iText is easy to learn, there's an astonishing range of things you can do once you dive below the surface. This book lowers the learning curve and, though numerous innovative and practical examples, unlocks the secrets hidden in Adobe's PDF Reference. The examples are in Java but they can be easily adapted to .NET using one of iText's .NET ports: iTextSharp or iText.NET. +
"The book provides all the theory and working programs needed to create real applications based on the latest IEEE P1363 standard." --Reviewed in Cryptologia +
Implementing PeopleSoft Financials discusses the issues that arise and the pitfalls to avoid. Every member of the implementation team--from entry-level accounting clerk through MIS staff to executive sponsors--will benefit from reading this book. +
Develop Notes and Domino Web applications by providing advanced LotusScript code for direct use in your programs. This book emphasizes practical, useable code and solutions to common Notes programming problems. +
This intermediate Java programming book provides Java programmers with the information and tools needed to create your own IM client and server software. +
Internet BBSs: A Guided Tour provides in-depth coverage of the new world of true BBSs now available world-wide. It is a valuable resource for anyone currently using the Internet. +
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"The best-thought-out and researched piece of literature on the jQuery library." --From the forward by John Resig, Creator of jQuery +
jQuery in Action, Second Edition is a fast-paced introduction to jQuery that will take your JavaScript programming to the next level. An in-depth rewrite of the bestselling first edition, this edition provides deep and practical coverage of the latest jQuery and jQuery UI releases. The book's unique "lab pages" anchor the explanation of each new concept in a practical example. You'll learn how to traverse HTML documents, handle events, perform animations, and add Ajax to your web pages. This comprehensive guide also teaches you how jQuery interacts with other tools and frameworks and how to build jQuery plugins. +
JUnit in Action, Second Edition is an up-to-date guide to unit testing Java applications (including Java EE applications) using the JUnit framework and its extensions. This book provides techniques for solving real-world problems such as testing AJAX applications, using mocks to achieve testing isolation, in-container testing for Java EE and database applications, and test automation. +
Java Applets and Channels Without Programming collects almost 100 applets on a CD with detailed instructions on how to use each applet. In addition, style issues are discussed in detail; not only will you learn how to use each applet, you will learn when and where it is appropriate to use each applet. The book also introduces the new concept of channels and shows how these can be used on your web site as well. +
The most widely used build tool for Java projects, Ant is cross-platform, extensible, simple, and fast. It scales from small personal projects to large, multi-team J2EE projects. And, most important, it's easy to learn. +
"...this book is the ultimate solution. If you are going to use Hibernate in your application, you have no other choice, go rush to the store and get this book." --JavaLobby +
Do Androids Dream of Electric Sheep? (retroactively retitled Blade Runner: Do Androids Dream of Electric Sheep? in some later printings) is a dystopian science fiction novel by American writer Philip K. Dick, first published in 1968. The novel is set in a post-apocalyptic San Francisco, where Earth's life has been greatly damaged by a nuclear global war, leaving most animal species endangered or extinct. The main plot follows Rick Deckard, a bounty hunter who is tasked with "retiring" (i.e. killing) six escaped Nexus-6 model androids, while a secondary plot follows John Isidore, a man of sub-par IQ who aids the fugitive androids. +
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Learn Windows PowerShell in a Month of Lunches is an innovative tutorial designed for busy administrators. Author Don Jones has taught thousands of administrators to use PowerShell, and now he'll teach you, bringing his years of training techniques to a concise, easy-to-follow book. Just set aside one hour a day lunchtime would be perfect for an entire month, and you'll be automating administrative tasks faster than you ever thought possible. Don combines his own in-the-trenches experience with years of PowerShell instruction to deliver the most important, effective, and engaging elements of PowerShell to you quickly and painlessly, setting you on the path to a career-boosting future. +
With clear writing, reusable examples, and unmatched advice on best practices, Lucene in Action is still the definitive guide to developing with Lucene. +
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Machine Learning in Action is a unique book that blends the foundational theories of machine learning with the practical realities of building tools for everyday data analysis. In it, you'll use the flexible Python programming language to build programs that implement algorithms for data classification, forecasting, recommendations, and higher-level features like summarization and simplification. +
"Distinctive book explaining how to get intelligent software agents to work." --Clipcode.com +
Making Java Groovy is a practical handbook for developers who want to blend Groovy into their day-to-day work with Java. It starts by introducing the key differences between Java and Groovy and how you can use them to your advantage. Then, it guides you step-by-step through realistic development challenges, from web applications to web services to desktop applications, and shows how Groovy makes them easier to put into production. +
Making Sense of Java clearly and concisely explains the concepts, features, benefits, potential, and limitations of Java. +
Microsoft Office Essentials simply covers the things you really want to know and skips over all those esoteric features that 99 out of 100 readers never use. +
Mobile Agents is the first book to give the reader the ability to create and use powerful mobile agents on the Internet. +
MongoDB In Action is a comprehensive guide to MongoDB for application developers. The book begins by explaining what makes MongoDB unique and describing its ideal use cases. A series of tutorials designed for MongoDB mastery then leads into detailed examples for leveraging MongoDB in e-commerce, social networking, analytics, and other common applications. +
With the detailed coverage of the entire set of protocols in Multiprotocol over ATM, you can be equal to the task. +
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Node.js in Action is an example-driven tutorial that starts at square one and guides you through all the features, techniques, and concepts you'll need to build production-quality Node applications. You'll start by learning how to set up your Node development environment, including loading the community-created extensions. Next, you'll run several simple demonstration programs where you'll learn the basics of a few common types of Node applications. Then you'll dive into asynchronous programming, a model Node leverages to lessen application bottlenecks. +
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OSGi in Action is a comprehensive guide to OSGi with two primary goals. First, it provides a clear introduction to OSGi concepts with examples that are relevant both for architects and developers. The central idea of OSGi is modularity, so you start by learning about OSGi bundles. You'll then see how OSGi handles module lifecycles and follow up with how it promotes service-oriented interaction among application components. +
Enterprise OSGi shows a Java developer how to develop to the OSGi Service Platform Enterprise specification, an emerging Java-based technology for developing modular enterprise applications. Enterprise OSGi addresses several shortcomings of existing enterprise platforms, such as allowing the creation of better maintainable and extensible applications, and provide a simpler, easier-to-use, light-weight solution to enterprise software development. +
Frameworks are object-oriented programming environments for vertical application areas. This book is the first to survey this exciting new technology, its concepts, and practical applications. +
Object Technology Centers of Excellence provides guidance to those charged with managing the shift to object technology. It is the only book on the market aimed not at the project level but at the corporate level, with a focus on the infrastructures necessary for a successful transition. +
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"If there was ever a textbook for software development in PHP, this would be it." Cal Evans, Podcast Review, Zend Developer Network +
Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized by club-like spikes that project from their surface, an unusually large RNA genome, and a unique replication strategy. Coronaviruses cause a variety of diseases in mammals and birds ranging from enteritis in cows and pigs and upper respiratory disease chickens to potentially lethal human respiratory infections. Here we provide a brief introduction to coronaviruses discussing their replication and pathogenicity, and current prevention and treatment strategies. We will also discuss the outbreaks of the highly pathogenic Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the recently identified Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV). +
Background Attaining the perfect balance of health care resources is ... +
Coronaviruses (CoVs) have formerly been regarded as relatively harmless respiratory pathogens to humans. However, two outbreaks of severe respiratory tract infection, caused by the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV), as a result of zoonotic CoVs crossing the species barrier, caused high pathogenicity and mortality rates in human populations. This brought CoVs global attention and highlighted the importance of controlling infectious pathogens at international borders. In this review, we focus on our current understanding of the epidemiology, pathogenesis, prevention, and treatment of SARS-CoV and MERS-CoV, as well as provides details on the pivotal structure and function of the spike proteins (S proteins) on the surface of each of these viruses. For building up more suitable animal models, we compare the current animal models recapitulating pathogenesis and summarize the potential role of host receptors contributing to diverse host affinity in various species. We outline the research still needed to fully elucidate the pathogenic mechanism of these viruses, to construct reproducible animal models, and ultimately develop countermeasures to conquer not only SARS-CoV and MERS-CoV, but also these emerging coronaviral diseases. +
Objectives To identify factors that predict repeat admission to hospital for adverse drug reactions (ADRs) in older adults. Design Population based retrospective cohort study. Setting All public and private hospitals in Western Australia. Participants 28 548 patients aged ≥60 years with an admission for an ADR during 1980-2000 followed for three years using the Western Australian data linkage system. Results 5056 (17.7%) patients had a repeat admission for an ADR. Repeat ADRs were associated with sex (hazard ratio 1.08, 95% confidence interval 1.02 to 1.15, for men), first admission in 1995-9 (2.34, 2.00 to 2.73), length of hospital stay (1.11, 1.05 to 1.18, for stays ≥14 days), and Charlson comorbidity index (1.71, 1.46 to 1.99, for score ≥7); 60% of comorbidities were recorded and taken into account in analysis. In contrast, advancing age had no effect on repeat ADRs. Comorbid congestive cardiac failure (1.56, 1.43 to 1.71), peripheral vascular disease (1.27, 1.09 to 1.48), chronic pulmonary disease (1.61, 1.45 to 1.79), rheumatological disease (1.65, 1.41 to 1.92), mild liver disease (1.48, 1.05 to 2.07), moderate to severe liver disease (1.85, 1.18 to 2.92), moderate diabetes (1.18, 1.07 to 1.30), diabetes with chronic complications (1.91, 1.65 to 2.22), renal disease (1.93, 1.71 to 2.17), any malignancy including lymphoma and leukaemia (1.87, 1.68 to 2.09), and metastatic solid tumours (2.25, 1.92 to 2.64) were strong predictive factors. Comorbidities requiring continuing care predicted a reduced likelihood of repeat hospital admissions for ADRs (cerebrovascular disease 0.85, 0.73 to 0.98; dementia 0.62, 0.49 to 0.78; paraplegia 0.73, 0.59 to 0.89). Conclusions Comorbidity, but not advancing age, predicts repeat admission for ADRs in older adults, especially those with comorbidities often managed in the community. Awareness of these predictors can help clinicians to identify which older adults are at greater risk of admission for ADRs and, therefore, who might benefit from closer monitoring.
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit α (PIK3CA) is a central element of a signaling pathway involved in cell proliferation, survival, and growth. Certain mutations in this pathway result in enhanced PI3K signaling, which is associated with oncogenic cellular transformation and cancer. The aims of this study were to characterize different types of PIK3CA mutations in exons 9 and 20 in a series of primary breast carcinomas and to correlate the results with clinicopathologic parameters and survival. We used frozen tissue samples and sequenced exons 9 and 20 for a series of 241 patients with a diagnosis of breast carcinoma. We found that 15.8% of the primary breast carcinomas possessed PIK3CA mutations in either exon 9 or exon 20. The rate of PIK3CA mutations was increased in HR(+)/HER2(-) tumors (18.6%), but this difference did not reach a statistical significance. The lowest rate of mutations was observed in HR(+)/HER2(+) tumors (5.3%). No statistically significant association was found between the presence of PIK3CA mutations and the prognostic/clinical features of breast cancer, including histologic subtype, Her2 status, axillary lymph node involvement, tumor grade, and tumor stage. However, the presence of the H1047R mutation in 10 samples was associated with a statistically significantly worse overall survival. PIK3CA mutation was found to be a frequent genetic change in all breast cancer subtypes but occurred with the highest rate in HR(+)/HER2(-) tumors. Further studies are needed to validate the prognostic impact of different PIK3CA mutations. +
Dermoscopy is increasingly used by clinicians (dermatologists, family physicians, podiatrists, doctors of osteopathic medicine, etc) to inform clinical management decisions. Dermoscopic findings or images provided to pathologists offer important insight into the clinician's diagnostic and management thought process. However, with limited dermoscopic training in dermatopathology, dermoscopic descriptions and images provided in the requisition form provide little value to pathologists. Most dermoscopic structures have direct histopathologic correlates, and therefore dermoscopy can act as an excellent communication bridge between the clinician and the pathologist. In the first article in this continuing medical education series, we review dermoscopic features and their histopathologic correlates.Copyright © 2018 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved. +
