Malignant melanoma

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Malignant melanoma
Malignant-melanoma-H-E-stain.jpg
Malignant melanoma. (H&E stain)
Classification
Has microscopic description: melanocytic differentiation (e.g. pigment)·abnormal architecture·lack of maturation·+/-nuclear atypia - esp. nucleoli·+/-upward scatter of melanocytes·+/-asymmetry of pigmentation
LMDDx Light microscopic DDx: dysplastic nevus·Spitz nevus·common nevus (nevoid melanoma)·atypical fibroxanthoma·(spindle cell) squamous cell carcinoma·leiomyosarcoma·serous carcinoma·clear cell sarcoma·others
Stains: melanin
IHC Immunohistochemical staining, also known as immunostaining: S-100·Melan A·HMB-45·MITF·tyrosinase
EM Electron microscopic features: melanosomes
Site Anatomical site: skin·sun exposed skin areas·oral mucosa·others
Syndromes Syndromes associated with the diagnosis: familial melanoma
Signs: ABCDE = asymmetrical·border irregular·colour (black)·diameter (>6 mm)·evolving (growing)
Prevalence: common
ClinDDx: pigmented skin lesions·melanocytic lesions

DISCLAIMER: Information has been copied from librepathology:malignantMelanoma and the Malignant melanoma page does not claim factual (or medical) correctness. It is to demonstrate how medical (or bio-related) subjects can be used, annotated, and exported (as RDF) via Semantic MediaWiki.

Malignant melanoma, also melanoma, is an aggressive type of skin cancer that can be diagnostically challenging for pathologists.

It fits into the larger category of melanocytic lesions which includes ...

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... davantage au sujet de « Malignant melanoma »
Malignant melanoma, also melanoma, is an aggressive type of skin cancer that can be diagnostically challenging for pathologists. It fits into the larger category of melanocytic lesions which includes ... +
melanocytic differentiation (e.g. pigment) +, abnormal architecture +, lack of maturation +, +/-nuclear atypia - esp. nucleoli +, +/-upward scatter of melanocytes +  et +/-asymmetry of pigmentation +
ABCDE = asymmetrical +, border irregular +, colour (black) +, diameter (>6 mm) +  et evolving (growing) +
... davantage au sujet de « Malignant melanoma »
 
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Date de modification
Est local
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10:22:19, 3 mai 2020
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