Malignant melanoma
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| Malignant melanoma | |
|---|---|
 Malignant melanoma. (H&E stain) | |
Classification
| |
| MicroMicroscopic description ᵖ: | melanocytic differentiation (e.g. pigment)·abnormal architecture·lack of maturation·+/-nuclear atypia - esp. nucleoli·+/-upward scatter of melanocytes·+/-asymmetry of pigmentation |
| LMDDx Light microscopic DDx: | dysplastic nevus·Spitz nevus·common nevus (nevoid melanoma)·atypical fibroxanthoma·(spindle cell) squamous cell carcinoma·leiomyosarcoma·serous carcinoma·clear cell sarcoma·others |
| Stains: | melanin |
| IHC Immunohistochemical staining, also known as immunostaining: | S-100·Melan A·HMB-45·MITF·tyrosinase |
| EM Electron microscopic features: | melanosomes |
| Site Anatomical site: | skin·sun exposed skin areas·oral mucosa·others |
| Syndromes Syndromes associated with the diagnosis: | familial melanoma |
| Signs: | ABCDE = asymmetrical·border irregular·colour (black)·diameter (>6 mm)·evolving (growing) |
| Prevalence: | common |
| ClinDDx: | pigmented skin lesions·melanocytic lesions |
DISCLAIMER: Information has been copied from 1 and the Malignant melanoma page does not claim factual (or medical) correctness. It is to demonstrate how medical (or bio-related) subjects can be used, annotated, and exported (as RDF) via Semantic MediaWiki.
Malignant melanoma, also melanoma, is an aggressive type of skin cancer that can be diagnostically challenging for pathologists.
It fits into the larger category of melanocytic lesions which includes ...
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Malignant melanoma, also melanoma, is an aggressive type of skin cancer that can be diagnostically challenging for pathologists.
It fits into the larger category of melanocytic lesions which includes ... +
MicroMicroscopic description ᵖ
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