Spitz nevus

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Spitz nevus

High magnification micrograph of a Spitz nevus, also known as an epithelioid and spindle-cell nevus. H&E stain.
Classification
Micro ᵖ: nests of cells·spindle·epithelioid·spindle/epithelioid (in both dermis and epidermis)·nests are vertically arranged ("hanging bananas")·+/-hyperkeratosis·+/-hypergranulosis·+/-acanthosis (thick stratum spinosum)·Kamino bodies - dense eosinophilic bodies (rare in melanoma)
LMDDx Light microscopic DDx: malignant melanoma·pigmented spindle cell nevus of Reed
Stains: HMB-45 -ve deep aspect·Ki-67 usu. low
Site Anatomical site: skin·skin face·extremity
Prevalence: uncommon
ClinDDx: melanoma·melanocytic lesions

Spitz nevus, also known as epithelioid and spindle cell nevus, is an uncommon melanocytic lesion that can be difficult to differentiate from malignant melanoma.1


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Spitz nevus, also known as epithelioid and spindle cell nevus, is an uncommon melanocytic lesion that can be difficult to differentiate from malignant melanoma +
Micro ᵖ
nests of cells +, spindle +, epithelioid +, spindle/epithelioid (in both dermis and epidermis) +, nests are vertically arranged ("hanging bananas") +, +/-hyperkeratosis +, +/-hypergranulosis +, +/-acanthosis (thick stratum spinosum) +  et Kamino bodies - dense eosinophilic bodies (rare in melanoma) +
Citation resourceCette propriété est une propriété spéciale dans ce wiki.
Citation referenceCette propriété est une propriété spéciale dans ce wiki.
librepathology:spitNevus +
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